OxyContin - Canadian Medical Guide
OxyContin

BRAND NAMES
NARCOTIC ANALGESICS
Buprenorphine, Codeine, Codeine & Terpinhydrate, Dihydrocodeine, Fentanyl, Hydrocodone, Hydrocodone & Homatropine, Hydromorphone, Levorphanol, Meperidine,  Methadone, Morphine, Nalbuphine, Opium, Oxycodone, Oxymorphone, Pentazocine, Propoxyphene


BASIC OxyContin INFO
Habit forming? Yes
Prescription needed? Yes
Available as generic? Yes
Drug class: Narcotic


OxyContin MEDICAL USES
Relieves pain and diarrhea; suppresses cough.


MEDICAL DOSAGE & OxyContin USAGE
How to take OxyContin:

- Tablet, capsule or extended release tablet: Swallow OxyContin with liquid. Do not crush, crumble or open extended release forms, especially the Palladona brand (could lead to a fatal dose).

- Liquid form of morphine: Mix with fruit juice just before taking to improve taste.

- Syrup: Mix with one-half glass of water (4 oz.) before swallowing.

- Dispersible tablets: Stir OxyContin into water or fruit juice just before taking each dose.

- Liquid form: May need to be diluted with water before taking. Follow directions on label.

- Suppositories: Remove wrapper and moisten suppository with water. Gently insert into rectum, small end first.

- Nasal, transmucosal, transdermal or lozenge form: Follow prescription instructions.

- Buccal tablet: Let tablet dissolve in mouth per instructions. Do not chew or swallow whole.


When to take OxyContin:

- When needed.

- No more often than every 4 hours.


If you forget a OxyContin dose:

- Take as soon as you remember. Wait 4 hours for next dose.


What OxyContin does:

- Blocks pain messages to brain and spinal cord.

- Reduces sensitivity of brain's cough control center.


Time lapse before drug works:

- 30 minutes.


Don't take OxyContin with:

- Any other medicine or any dietary supplement without consulting your doctor or pharmacist.


OxyContin OVERDOSE
SYMPTOMS: Deep sleep, slow breathing; slow pulse; respiratory arrest; flushed, warm skin; seizures; constricted pupils.
OxyContin SIDE EFFECTS

Life-threatening:

Irregular or slow heartbeat, difficult breathing, wheezing.

Common OxyContin Side Effects:

Dizziness, drowsiness, tiredness, headache, lightheadedness, nausea or vomiting, stomach cramps, overexcitement.

Infrequent OxyContin Side Effects:

Black, tarry stools; bloody or cloudy urine; painful or frequent urination; fast, slow or pounding heartbeat; hallucinations; breathing problems, wheezing; back or side pain; red dots on skin; red or flushed face; ringing or buzzing in ears; skin rash, hives or itching; sore throat; fever; face swelling; decreased urine; trembling; uncontrolled muscle movements; unusual bleeding or bruising; yellow skin or eyes. Feeling depressed,

Rare OxyContin Side Effects:

Changes in vision, constipation, dry mouth, loss of appetite, restlessness, nightmares, trouble sleeping.
PRECAUTIONS

Don't take OxyContin if:  
- You are allergic to any narcotic.

- Diarrhea is due to toxic effect of drugs or poisons.


Before you start, consult your doctor if:

- You have impaired liver or kidney function.
- You will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.

- You have asthma.


Over age 60:

- More likely to be drowsy, dizzy, unsteady or constipated.

- Use only if absolutely necessary.


Pregnancy:

- Risk factors vary for drugs in this group. Consult doctor.


Breast-feeding:

- Drug filters into milk. OxyContin may harm child. Avoid.


Infants & children:

- OxyContin is not recommended.


Prolonged OxyContin use:

- With high doses and long-term use, can cause psychological and physical dependence (addiction).

- May cause chronic constipation.


Skin & sunlight:

- No special problems expected.


Driving, piloting or hazardous work:

- Don't drive or pilot aircraft until you learn how medicine affects you.

- Don't work around dangerous machinery.

- Don't climb ladders or work in high places.

- Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs.


Discontinuing OxyContin:

- Discontinue in 2 days if symptoms don't improve.

- Report to the doctor any symptoms that develop after discontinuing, such as gooseflesh, irritability, insomnia, yawning, weakness, large eye pupils.

- If used for several weeks or more, consult doctor before discontinuing.


Others:

- Some products contain tartrazine dye. Avoid, especially if you are allergic to aspirin.

- Advise any doctor or dentist whom you consult that you take this medicine.

- Follow directions exactly for using the fentanyl skin patch to avoid an overdose that could lead to severe side effects (including death).

- Lying down after the first few doses may decrease unwanted effects of nausea, vomiting, lightheadedness or dizziness.
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POSSIBLE INTERACTIONS WITH OTHER DRUGS / SUBSTANCES

POSSIBLE INTERACTION WITH OTHER DRUGS

Analgesics/Other: Increased analgesic effect.

Anticoagulants,Oral: Possible increased anticoagulant effect.

Anticholinergics: Increased anticholinergic effect.

Antidepressants: Increased sedative effect.

Antihistamines: Increased sedative effect.

Anti-inflammatory drugs, non-steroidal (NSAIDs): Increased narcotic effect.

Butorphanol: Possibly precipitates withdrawal with chronic narcotic use.

Carbamazepine: Increased carbamazepine effect possible with propoxyphene.

Carteolol: Increased narcotic effect. Dangerous sedation.

Cimetidine: Possible increased narcotic effect and toxicity.

Guanfacine: May increase depressant effects of either drug.

Clozapine: Toxic effect on the central nervous system.

Ethinamate: Dangerous increased effects of ethinamate. Avoid combining.

Fluoxetine: Increased depressant effects of both drugs.

Leucovorin: High alcohol content of leucovorin may cause adverse effects.

Methyprylon: Increased sedative effect, perhaps to dangerous level. Avoid.

Metformin: Increased effect of metformin with morphine.

Pentazocine: Possibly precipitates withdrawal with chronic narcotic use.

Mind-altering drugs: Increased sedative effect.

Molindone: Increased narcotic effect.

Monoamine oxidase (MAO) Inhibitors: Serious toxicity (including death).

Nabilone: Greater depression of central nervous system.

Nalbuphine: Possibly precipitates withdrawal with chronic narcotic use.

Naltrexone: Precipitates with-drawal symptoms. May lead to respiratory arrest, coma and death.

Narcotics/Other: Increased narcotic effect.

Nicotine: Increased effect of pentazocine and propoxyphene.

Nitrates: Excessive blood pressure drop.

Phenothlazines: Increased sedative effect.

Phenytoin: Possible decreased narcotic effect.

Rifamycins: Possible decreased narcotic effect.

Sedatives: Increased sedative effect.

Selegiline: Severe toxicity characterized by breathing difficulties, seizures, coma.

Sertraline: Increased depressive effects of both drugs.

Sleep Inducers: Increased sedative effect.

Sotalol: Increased narcotic effect. Dangerous sedation.

Tramadol: Increased sedation.

Tranquilizers: Increased sedative effect.


POSSIBLE INTERACTION WITH OTHER SUBSTANCES

Alcohol:
Increased intoxicating effect of alcohol (especially Avinza brand). Do not drink alcohol or take alcohol-containing drugs.

Beverages: None expected.

Cocaine: Increased toxic effects of cocaine. Avoid.

Foods: None expected.

Marijuana: Impaired physical and mental perfor-mance. Avoid.

Tobacco: None expected.

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