CELEBREX - Canadian Medical Guide
CELEBREX

BRAND NAMES
ANTI-INFLAMMATORY DRUGS, NONSTEROIDAL (NSAIDs) COX-2 INHIBITORS
Celebrex
ROFECOXIB
VALDECOXIB


BASIC CELEBREX INFO
Habit forming? No
Prescription needed? Yes
Available as generic? No
Drug class: Anti-Inflammatory (non-steroidal), analgesic, anti-gout agent, fever-reducer


MEDICAL USES
Treatment for joint pain, stiffness, inflammation and swelling of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and gout.

- Treatment for pain, fever and inflammation.

- Treatment for dysmenorrhea (painful or difficult menstruation).

- Treatment for colorectal polyps.

- Special note: This class of drugs has been linked to an increased risk of heart attack and stroke. Consult doctor before using.




MEDICAL DOSAGE & CELEBREX USAGE
How to take Celebrex:

- Tablet or capsule: Swallow with liquid. If you can't swallow whole, open capsule or crumble tablet and take with liquid or food.

- Suspension: Shake the bottle well before use. Carefully measure dose with measuring spoon or cup.


When to take Celebrex:

- At the same times each day.


If you forget a dose:

- Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).


What drug does:

- Reduces tissue concentration of prostaglandins (Hormones which produce inflammation and pain).


Time lapse before drug works:

- Begins in 2 to 3 hours. May require 3 weeks of regular use for maximum benefit.


Don't take with:

- Any other medicine or any dietary supplement without consulting your doctor or pharmacist.
 


CELEBREX OVERDOSE
SYMPTOMS: Breathing problems, tightness in chest, Decreased urine amount, swelling, thirst, Tiredness or weakness, stomach pain, bloody or black stools, dizziness, headache, nausea or vomiting.
CELEBREX SIDE EFFECTS

Life-threatening:

Hives, rash, intense itching, faintness soon after a dose (anaphylaxis in aspirin-sensitive persons).

Common Celebrex Side Effects:

Cough, fever, skin rash, swelling of face, fingers, feet and/or lower legs. Back pain, dizziness, gas, headache, nausea, and heartburn, burning in throat, sleeplessness, stuffy or runny nose.

Infrequent Celebrex Side Effects:

Bloody or tarry stools, chills, congestion, diarrhea, fatigue, loss of appetite, muscle pains, blood in urine, pale skin, shortness of breath, severe stomach pain, weight gain, vomiting. o Anxiety, vision changes, noises in ears, changes in sense of taste, difficulty swallowing, dry mouth, constipation, depression, rapid heartbeat, increased sweating, numbness in fingers or toes, sleepiness.

Rare Celebrex Side Effects:

None expected.
PRECAUTIONS

Others:

- May affect results in some medical tests.

- Advise any doctor or dentist whom you consult that you take this medicine.
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POSSIBLE INTERACTIONS WITH OTHER DRUGS / SUBSTANCES

POSSIBLE INTERACTION WITH OTHER DRUGS

Anglotensin-converting enzyme (ACE) inhibitors: May decrease ACE inhibitor effect.

Antacids: Decreased pain relief.

Antifungals, azole: Increased risk of side effects.

Anti-Inflammatory drugs, non-steroidal (NSAIDs) other: Increased risk of side effects.

Aspirin: Increased risk of stomach ulcer.

Dextromethorphan: Increased effect of dextromethorphan.

Diuretics: Decreased diuretic effect.

Lithium: Increased lithium effect.

Methotrexate: Increased methotrexate effect.

Phenytoin: Decreased pain relief.

Rifampin: Decreased Rifampin effect.

Warfarin: Increased risk of bleeding problems.


POSSIBLE INTERACTION WITH OTHER SUBSTANCES

Alcohol: Possible stomach ulcer or bleeding.

Beverages: None expected.

Cocaine: None expected.

Foods: None expected.

Marijuana: May increase pain relief.

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