Canadian Medical Guide > Chemicals and Drugs > Organic Chemicals > Aza Compounds Terms and Definitions

Aza Compounds

	Azacitidine - A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.
	Azaguanine - One of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
	Azauridine - A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.

Aza Compounds Medical Definitions and Terms