DNA Repeat Expansion
| Medical Definition: |
An increase number of repeats of a genomic, tandemly repeated DNA sequence from one generation to the next. |
| Also Called: |
Expanded DNA Repeats |
| Previously Indexed: |
Repetitive Sequences, Nucleic Acid or specifics (1993-2003) |
DNA Repeat Expansion Categories.
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Trinucleotide Repeat Expansion - An increased number of contiguous trinucleotide repeats in the DNA sequence from one generation to the next. The presence of these regions is associated with diseases such as FRAGILE X SYNDROME and MYOTONIC DYSTROPHY. Some CHROMOSOME FRAGILE SITES are composed of sequences where trinucleotide repeat expansion occurs. |
DNA Repeat Expansion Medical Definitions and Terms
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