Immunologic Deficiency Syndromes
| Medical Definition: |
Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral. |
| Guide Notes: |
GEN or unspecified; for defic of specific immunoprotein, IMMUNOGLOBULINS or specific immunoglobulin, use specific with /defic; TN 223: definition & use; TN 225: differentiation from immunoglobulin defic; Manual 23.25.2; DF: IMMUNOL DEFIC SYNDROMES |
| Also Called: |
Antibody Deficiency Syndrome |
| Previously Indexed: |
Immunity (1966-1967) |
Immunologic Deficiency Syndromes Categories.
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Common Variable Immunodeficiency - Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections. |
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Leukocyte-Adhesion Deficiency Syndrome - Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection. |
Immunologic Deficiency Syndromes Medical Definitions and Terms
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