Canadian Medical Guide > Chemicals and Drugs > Organic Chemicals > Amines > Propylamines Terms and Definitions

Propylamines

	Citalopram - A furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.
	Clorgyline - An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
	Fluoxetine - The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
	Mexiletine - Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
	Promethazine - A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
	Tranylcypromine - A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)

Propylamines Medical Definitions and Terms